Prednisolone (Orapred, Pred Forte, Prelone)

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Prescriptions: NO

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Group: corticosteroid Tablet, 5 mg General information Prednisolone is a synthetic glucocorticoid with weak mineralocorticoid properties. Its therapeutic effects result from inhibition of macrophage accumulation, suppression of capillary wall permeability, and reduction of fibroblast proliferation and collagen deposition. Clinical information Uses: Treatment of neuritis in leprosy patients. Treatment of inflammation in the eye in leprosy patients. Oral prednisolone treatment is then gradually reduced each week or every second week and is stopped after 12 weeks of treatment. The standard 12 week oral prednisolone treatment for an adult patient follows: Contraindications: Active bacterial, viral or fungal infections. Precautions: Patients must remain under close medical supervision. Body weight, blood pressure, fluid and electrolyte balance, and blood glucose concentrations should be monitored throughout treatment.

Read all of this leaflet carefully before you start taking this medicine. WHAT SOLUBLE PREDNISOLONE TABLETS ARE AND WHAT THEY ARE USED FOR The name of your medicine is Soluble Prednisolone Tablets. It provides a summary of the information available on your medicine. Soluble Prednisolone Tablets are used to treat a variety of inflammatory diseases including severe asthma, rheumatoid arthritis, allergic reactions, bowel diseases, severe skin conditions, kidney disorders and some blood disorders. Tell your doctor immediately if you have come into contact with anyone suffering with measles, chickenpox or shingles in the last three months. If you have any questions or are not sure about anything ask your doctor or pharmacist. It includes other important information on the safe and effective use of this medicine that may be especially important for you. If any of the above applies to you, or you are not sure please tell your doctor or pharmacist before you use this medicine. If you feel unwell in any way, keep taking your tablets, but see your doctor straight away. Prednisolone belongs to a group of medicines called steroids. Prednisolone reduces this inflammation, which could otherwise go on making your condition worse. However, if problems do occur they might need treatment. You must take this medicine regularly to get maximum benefit from it. What Soluble Prednisolone Tablets are and what they are used for 2. This is particularly important if you are depressed or might be thinking about suicide. In a few cases, mental health problems have happened when doses are being lowered or the medicine stopped altogether. Taking other medicines Please tell your doctor if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.

Allergy and anaphylaxis: bronchial asthma, drug hypersensitivity reactions, serum sickness, angioneurotic oedema, anaphylaxis, incapacitating allergies unresponsive to conventional treatment. Renal disorders: lupus nephritis, acute interstitial nephritis, minimal change glomerulonephritis, nephrotic syndrome. Endocrine disorders: primary and secondary adrenal insufficiency, congenital adrenal hyperplasia. Respiratory disease: allergic pneumonitis, asthma, occupational asthma, pulmonary aspergillosis, pulmonary fibrosis, pulmonary alveolitis, aspiration of foreign body, aspiration of stomach contents, pulmonary sarcoid, drug induced lung disease, adult respiratory distress syndrome, spasmodic croup, fulminating or disseminated pulmonary tuberculosis when used concurrently with appropriate antituberculosis chemotherapy. Rheumatic disorders: rheumatoid arthritis, polymyalgia rheumatica, juvenile chronic arthritis, psoriatic arthritis, systemic lupus erythematosus, dermatomyositis, mixed connective tissue disease. Skin disorders: pemphigus vulgaris, exfoliative dermatitis, bullous pemphigoid, systemic lupus erythematosus, pyoderma gangrenosum. Adults and the elderly The lowest effective dose should be used for the minimum period. Children Prednisolone should only be used when specifically indicated, at the lowest dose possible and for the shortest possible time. patients with rheumatoid arthritis with pronounced morning stiffness where an evening dose may need to be given. The initial dosage of Prednisolone may vary from 5mg to 60mg daily depending on the disorder being treated. The following therapeutic guidelines should be kept in mind for all therapy with corticosteroids: The lowest dose to produce an acceptable result should be given.

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